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Formal Neuropsychological Testing

Test Batteries, Interpretation, and Added Value in Practice
  • Victor A. Del Bene
    Affiliations
    Department of Neurology, Division of Neuropsychology, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL 35294, USA

    The Evelyn F. McKnight Brain Institute, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL 35294, USA
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  • Adam Gerstenecker
    Affiliations
    Department of Neurology, Division of Neuropsychology, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL 35294, USA

    The Evelyn F. McKnight Brain Institute, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL 35294, USA
    Search for articles by this author
  • Ronald M. Lazar
    Correspondence
    Corresponding author. Department of Neurology, The UAB Evelyn F. McKnight Brain Institute, University of Alabama at Birmingham, Birmingham, AL 35233.
    Affiliations
    Department of Neurology, Division of Neuropsychology, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL 35294, USA

    The Evelyn F. McKnight Brain Institute, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL 35294, USA

    Department of Neurobiology, University of Alabama at Birmingham Heersink School of Medicine, Birmingham, AL 35294, USA
    Search for articles by this author
Published:October 18, 2022DOI:https://doi.org/10.1016/j.cger.2022.07.003

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      References

        • Sweet J.J.
        • Klipfel K.M.
        • Nelson N.W.
        • et al.
        Professional practices, beliefs, and incomes of US neuropsychologists: the AACN, NAN, SCN 2020 practice and “salary survey”.
        Clin Neuropsychologist. 2021; 35: 7-80
        • Lezak M.D.
        • Howieson D.B.
        • Loring D.W.
        • et al.
        Neuropsychological assessment.
        Oxford University Press, USA2004
        • Vakil E.
        Neuropsychological assessment: Principles, rationale, and challenges.
        J Clin Exp Neuropsychol. 2012; 34: 135-150
        • Barr W.B.
        Historical development of the neuropsychological test battery.
        Textbook Clin Neuropsychol. 2008; : 3-17
        • Price C.J.
        The evolution of cognitive models: from neuropsychology to neuroimaging and back.
        Cortex. 2018; 107: 37-49
        • Assuras S.
        • Levin B.
        Special considerations for the neuropsychological interview with older adults. Handbook on the Neuropsychology of Aging and Dementia.
        Springer, 2013: 3-9
        • Block C.K.
        • Johnson-Greene D.
        • Pliskin N.
        • et al.
        Discriminating cognitive screening and cognitive testing from neuropsychological assessment: implications for professional practice.
        Clin Neuropsychologist. 2017; 31: 487-500
        • Roebuck-Spencer T.M.
        • Glen T.
        • Puente A.E.
        • et al.
        Cognitive screening tests versus comprehensive neuropsychological test batteries: a national academy of neuropsychology education paper.
        Arch Clin Neuropsychol. 2017; 32: 491-498
        • Chan E.
        • Khan S.
        • Oliver R.
        • et al.
        Underestimation of cognitive impairments by the Montreal Cognitive Assessment (MoCA) in an acute stroke unit population.
        J Neurol Sci. 2014; 343: 176-179
        • Moafmashhadi P.
        • Koski L.
        Limitations for interpreting failure on individual subtests of the Montreal Cognitive Assessment.
        J Geriatr Psychiatry Neurol. 2013; 26: 19-28
        • Garrett K.D.
        • Perry W.
        • Williams B.
        • et al.
        Cognitive screening tools for late career physicians: a critical review.
        J Geriatr Psychiatry Neurol. 2021; 34: 171-180
        • Gaudet C.E.
        • Del Bene V.A.
        Neuropsychological assessment of the aging physician: a review and commentary.
        J Geriatr Psychiatry Neurol. 2021; 35: 271-279
        • Del Bene V.A.
        • Brandt J.
        Identifying neuropsychologically impaired physicians.
        Clin Neuropsychologist. 2020; 34: 318-331
        • Heaton R.K.
        • Ryan L
        • Grant I.
        Demographic influences and use of demographically corrected norms in neuropsychological assessment.
        in: Grant I. Adams K.M. Neuropsychological Assessment of Neuropsychiatric and Neuromedical Disorders. 3rd ed. Oxford University Press, New York2019: 127-158
        • Testa S.M.
        • Winicki J.M.
        • Pearlson G.D.
        • et al.
        Accounting for estimated IQ in neuropsychological test performance with regression-based techniques.
        J Int Neuropsychol Soc. 2009; 15: 1012-1022
        • Graf C.
        The Lawton instrumental activities of daily living scale.
        AJN The Am J Nurs. 2008; 108: 52-62
        • Iverson G.L.
        • Brooks B.L.
        • White T.
        • Stern R.A.
        Neuropsychological Assessment Battery (NAB): Introduction and advanced interpretation.
        in: Horton Jr A.M. Wedding D. The Neuropsychology Handbook. Springer Publishing Inc, New York2008: 279-343
        • Cullum C.M.
        • Saine K.
        • Chan L.D.
        • et al.
        Performance-based instrument to assess functional capacity in dementia: the Texas Functional Living Scale.
        Cogn Behav Neurol. 2001; 14: 103-108
        • Gerstenecker A.
        • Eakin A.
        • Triebel K.
        • et al.
        Age and education corrected older adult normative data for a short form version of the Financial Capacity Instrument.
        Psychol Assess. 2016; 28: 737
        • Malloy P.
        • Tremont G.
        • Grace J.
        • et al.
        The Frontal Systems Behavior Scale discriminates frontotemporal dementia from Alzheimer’s disease.
        Alzheimer's Demen. 2007; 3: 200-203
        • Kaufer D.I.
        • Cummings J.L.
        • Ketchel P.
        • et al.
        Validation of the NPI-Q, a brief clinical form of the Neuropsychiatric Inventory.
        J neuropsychiatry Clin neurosciences. 2000; 12: 233-239
      1. Strauss E., Sherman, E.M.S., et al., Compendium of neuropsychological tests: administration, norms, and commentary. 3rd ed. Oxford UK: Oxford University Press, 2006.

        • Scherr M.
        • Kunz A.
        • Doll A.
        • et al.
        Ignoring floor and ceiling effects may underestimate the effect of carotid artery stenting on cognitive performance.
        J neurointerventional Surg. 2016; 8: 747-751
        • Shura R.D.
        • Ord A.S.
        • Martindale S.L.
        • et al.
        Test of Premorbid Functioning: you’re doing it wrong, but does it matter?.
        Arch Clin Neuropsychol. 2022; 37: 1035-1040
        • Mullen C.M.
        • Fouty H.E.
        Comparison of the WRAT4 reading subtest and the WTAR for estimating premorbid ability level.
        Appl Neuropsychol Adult. 2014; 21: 69-72
        • Sweet J.J.
        • Heilbronner R.L.
        • Morgan J.E.
        • et al.
        American Academy of Clinical Neuropsychology (AACN) 2021 consensus statement on validity assessment: Update of the 2009 AACN consensus conference statement on neuropsychological assessment of effort, response bias, and malingering.
        The Clin Neuropsychologist. 2021; 35: 1053-1106
        • Bush S.S.
        • Ruff R.M.
        • Tröster A.I.
        • et al.
        Symptom validity assessment: practice issues and medical necessity NAN policy & planning committee.
        Arch Clin Neuropsychol. 2005; 20: 419-426
        • Bigler E.D.
        Effort, symptom validity testing, performance validity testing and traumatic brain injury.
        Brain Inj. 2014; 28: 1623-1638
        • Maiman M.
        • Del Bene V.A.
        • MacAllister W.S.
        • et al.
        Reliable digit span: does it adequately measure suboptimal effort in an adult epilepsy population?.
        Arch Clin Neuropsychol. 2019; 34: 259-267
        • McWhirter L.
        • Ritchie C.W.
        • Stone J.
        • et al.
        Performance validity test failure in clinical populations—a systematic review.
        J Neurol Neurosurg Psychiatr. 2020; 91: 945-952
        • Martin P.K.
        • Schroeder R.W.
        • Olsen D.H.
        Performance validity in the dementia clinic: specificity of validity tests when used individually and in aggregate across levels of cognitive impairment severity.
        The Clin Neuropsychologist. 2022; 36: 165-188
        • Clark H.
        • Martin P.
        • Schroeder R.
        Digit span Forward as a performance validity test in dementia evaluations: specificity in mild cognitive impairment, mild dementia, and moderate dementia.
        Arch Clin Neuropsychol. 2019; 34: 837
        • Corriveau-Lecavalier N.
        • Alden E.C.
        • Stricker N.H.
        • et al.
        Failed performance on the test of memory malingering and Misdiagnosis in individuals with early-onset Dysexecutive Alzheimer’s disease.
        Arch Clin Neuropsychol. 2022; https://doi.org/10.1093/arclin/acac016
        • Mitrushina M.
        • Boone K.B.
        • Razani J.
        • et al.
        Handbook of normative data for neuropsychological assessment.
        Oxford University Press, 2005
        • Duff K.
        Evidence-based indicators of neuropsychological change in the individual patient: relevant concepts and methods.
        Arch Clin Neuropsychol. 2012; 27: 248-261
        • Binder L.M.
        • Iverson G.L.
        • Brooks B.L.
        To err is human:“Abnormal” neuropsychological scores and variability are common in healthy adults.
        Arch Clin Neuropsychol. 2009; 24: 31-46
        • Reckess G.Z.
        • Varvaris M.
        • Gordon B.
        • et al.
        Within-person distributions of neuropsychological test scores as a function of dementia severity.
        Neuropsychology. 2014; 28: 254
        • Holtzer R.
        • Verghese J.
        • Wang C.
        • et al.
        Within-person across-neuropsychological test variability and incident dementia.
        Jama. 2008; 300: 823-830
        • Vance D.E.
        • Del Bene V.A.
        • Frank J.S.
        • et al.
        Cognitive intra-individual variability in HIV: an Integrative review.
        Neuropsychol Rev. 2021; : 1-22
        • Johnen A.
        • Bertoux M.
        Psychological and cognitive markers of behavioral variant frontotemporal dementia–A clinical neuropsychologist's view on diagnostic criteria and beyond.
        Front Neurol. 2019; 10: 594
        • Hutchinson A.
        • Mathias J.
        Neuropsychological deficits in frontotemporal dementia and Alzheimer’s disease: a meta-analytic review.
        J Neurol Neurosurg Psychiatry. 2007; 78: 917-928
        • Thompson J.C.
        • Stopford C.L.
        • Snowden J.S.
        • et al.
        Qualitative neuropsychological performance characteristics in frontotemporal dementia and Alzheimer’s disease.
        J Neurol Neurosurg Psychiatry. 2005; 76: 920-927
        • Foldi N.S.
        • Brickman A.M.
        • Schaefer L.A.
        • et al.
        Distinct serial position profiles and neuropsychological measures differentiate late life depression from normal aging and Alzheimer's disease.
        Psychiatry Res. 2003; 120: 71-84
        • Howieson D.
        Current limitations of neuropsychological tests and assessment procedures.
        The Clin Neuropsychologist. 2019; 33: 200-208
        • Manly J.J.
        Critical issues in cultural neuropsychology: Profit from diversity.
        Neuropsychol Rev. 2008; 18: 179-183
        • Brickman A.M.
        • Cabo R.
        • Manly J.J.
        Ethical issues in cross-cultural neuropsychology.
        Appl Neuropsychol. 2006; 13: 91-100
        • Pedraza O.
        • Mungas D.
        Measurement in cross-cultural neuropsychology.
        Neuropsychol Rev. 2008; 18: 184-193
        • Arce Rentería M.
        • Casalletto K.
        • Tom S.
        • et al.
        The contributions of active Spanish-English bilingualism to cognitive reserve among older hispanic adults living in California.
        Arch Clin Neuropsychol. 2019; 34: 1235
        • Tan Y.W.
        • Burgess G.H.
        • Green R.J.
        The effects of acculturation on neuropsychological test performance: a systematic literature review.
        The Clin Neuropsychologist. 2021; 35: 541-571
      2. Fujii D, Santos O, Della Malva L. Interpreter-assisted neuropsychological assessment: clinical considerations. Understanding cross-cultural neuropsychology: Science, testing and challenges. 2022.

        • Manly J.J.
        • Byrd D.A.
        • Touradji P.
        • et al.
        Acculturation, reading level, and neuropsychological test performance among African American elders.
        Appl Neuropsychol. 2004; 11: 37-46
        • Lennon J.C.
        • Aita S.L.
        • Del Bene V.A.
        • et al.
        Black and White individuals differ in dementia prevalence, risk factors, and symptomatic presentation.
        Alzheimer's & Dementia, 2021
        • Werry A.E.
        • Daniel M.
        • Bergström B.
        Group differences in normal neuropsychological test performance for older non-Hispanic White and Black/African American adults.
        Neuropsychology. 2019; 33: 1089
        • Thames A.D.
        • Hinkin C.H.
        • Byrd D.A.
        • et al.
        Effects of stereotype threat, perceived discrimination, and examiner race on neuropsychological performance: simple as black and white?.
        J Int Neuropsychological Soc. 2013; 19: 583-593
        • Manly J.J.
        • Echemendia R.J.
        Race-specific norms: using the model of hypertension to understand issues of race, culture, and education in neuropsychology.
        Arch Clin Neuropsychol. 2007; 22: 319-325
        • Manly J.J.
        • Jacobs D.M.
        • Touradji P.
        • et al.
        Reading level attenuates differences in neuropsychological test performance between African American and White elders.
        J Int Neuropsychological Soc. 2002; 8: 341-348
        • Glen T.
        • Hostetter G.
        • Roebuck-Spencer T.M.
        • et al.
        Return on investment and value research in neuropsychology: a call to arms.
        Arch Clin Neuropsychol. 2020; 35: 459-468
        • McGovern R.A.
        • Nelp T.B.
        • Kelly K.M.
        • et al.
        Predicting cognitive improvement in normal pressure hydrocephalus patients using preoperative neuropsychological testing and cerebrospinal fluid biomarkers.
        Neurosurgery. 2019; 85: E662-E669
        • Voon V.
        • Kubu C.
        • Krack P.
        • et al.
        Deep brain stimulation: neuropsychological and neuropsychiatric issues.
        Movement Disord official J Movement Disord Soc. 2006; 21: S305-S327
        • Gelb S.R.
        • Shapiro R.
        • Thornton W.
        Predicting medication adherence and employment status following kidney transplant: the relative utility of traditional and everyday cognitive approaches.
        Neuropsychology. 2010; 24: 514
        • Cormack F.
        • Shipolini A.
        • Awad W.I.
        • et al.
        A meta-analysis of cognitive outcome following coronary artery bypass graft surgery.
        Neurosci Biobehav Rev. 2012; 36: 2118-2129
        • Welmerink D.B.
        • Longstreth Jr., W.
        • Lyles M.F.
        • et al.
        Cognition and the risk of hospitalization for serious falls in the elderly: results from the Cardiovascular Health Study.
        Journals Gerontol Ser A: Biomed Sci Med Sci. 2010; 65: 1242-1249
        • Greysen S.R.
        • Cenzer I.S.
        • Auerbach A.D.
        • et al.
        Functional impairment and hospital readmission in Medicare seniors.
        JAMA Intern Med. 2015; 175: 559-565
        • Lyon D.
        • Lancaster G.A.
        • Taylor S.
        • et al.
        Predicting the likelihood of emergency admission to hospital of older people: development and validation of the Emergency Admission Risk Likelihood Index (EARLI).
        Fam Pract. 2007; 24: 158-167
        • Marioni R.E.
        • Proust-Lima C.
        • Amieva H.
        • et al.
        Cognitive lifestyle jointly predicts longitudinal cognitive decline and mortality risk.
        Eur J Epidemiol. 2014; 29: 211-219
        • Donders J.
        The incremental value of neuropsychological assessment: a critical review.
        The Clin Neuropsychologist. 2020; 34: 56-87
        • Leto L.
        • Feola M.
        Cognitive impairment in heart failure patients.
        J Geriatr Cardiol JGC. 2014; 11: 316
        • Svendsboe E.
        • Terum T.
        • Testad I.
        • et al.
        Caregiver burden in family carers of people with dementia with Lewy bodies and Alzheimer's disease.
        Int J Geriatr Psychiatry. 2016; 31: 1075-1083
        • Hu P.
        • Yang Q.
        • Kong L.
        • et al.
        Relationship between the anxiety/depression and care burden of the major caregiver of stroke patients.
        Medicine. 2018; 97