Advertisement
Review Article| Volume 32, ISSUE 3, P555-570, August 2016

Download started.

Ok

Bone and Joint Infections in Older Adults

Published:April 01, 2016DOI:https://doi.org/10.1016/j.cger.2016.02.003

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.

      Content published before 2002 is available via pay-per-view purchase only.

      Subscribe:

      Subscribe to Clinics in Geriatric Medicine
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Cierny 3rd, G.
        • Mader J.T.
        • Penninck J.J.
        A clinical staging system for adult osteomyelitis.
        Clin Orthop Relat Res. 2003; : 7-24
        • Bandeen-Roche K.
        • Seplaki C.L.
        • Huang J.
        • et al.
        Frailty in older adults: a nationally representative profile in the United States.
        J Gerontol A Biol Sci Med Sci. 2015; 70: 1427-1434
        • Makary M.A.
        • Segev D.L.
        • Pronovost P.J.
        • et al.
        Frailty as a predictor of surgical outcomes in older patients.
        J Am Coll Surg. 2010; 210: 901-908
        • Higuera C.A.
        • Elsharkawy K.
        • Klika A.K.
        • et al.
        2010 Mid-America Orthopaedic Association Physician in Training Award: predictors of early adverse outcomes after knee and hip arthroplasty in geriatric patients.
        Clin Orthop Relat Res. 2011; 469: 1391-1400
        • Eeles E.M.
        • White S.V.
        • O'Mahony S.M.
        • et al.
        The impact of frailty and delirium on mortality in older inpatients.
        Age Ageing. 2012; 41: 412-416
        • Frush T.J.
        • Noyes F.R.
        Baker's cyst: diagnostic and surgical considerations.
        Sports Health. 2015; 7: 359-365
        • Papadopoulos A.
        • Karachalios T.S.
        • Malizos C.N.
        • et al.
        Complicated septic arthritis after knee arthroscopy in a 75-year-old man with osteoarthritis and a popliteal cyst.
        BMJ Case Rep. 2015; 2015 ([pii:bcr2014207394])
        • Cassat J.E.
        • Smeltzer M.S.
        • Lee C.Y.
        Investigation of biofilm formation in clinical isolates of Staphylococcus aureus.
        Methods Mol Biol. 2014; 1085: 195-211
        • Gbejuade H.O.
        • Lovering A.M.
        • Webb J.C.
        The role of microbial biofilms in prosthetic joint infections.
        Acta Orthop. 2015; 86: 147-158
        • Dubost J.J.
        • Couderc M.
        • Tatar Z.
        • et al.
        Three-decade trends in the distribution of organisms causing septic arthritis in native joints: single-center study of 374 cases.
        Joint Bone Spine. 2014; 81: 438-440
        • Salar O.
        • Baker B.
        • Kurien T.
        • et al.
        Septic arthritis in the era of immunosuppressive treatments.
        Ann R Coll Surg Engl. 2014; 96: e11-e12
        • Roberts J.
        • Schaefer E.
        • Gallo R.A.
        Indicators for detection of septic arthritis in the acutely swollen joint cohort of those without joint prostheses.
        Orthopedics. 2014; 37: e98-e102
        • Li S.F.
        • Henderson J.
        • Dickman E.
        • et al.
        Laboratory tests in adults with monoarticular arthritis: can they rule out a septic joint?.
        Acad Emerg Med. 2004; 11: 276-280
        • Carpenter C.R.
        • Schuur J.D.
        • Everett W.W.
        • et al.
        Evidence-based diagnostics: adult septic arthritis.
        Acad Emerg Med. 2011; 18: 781-796
        • Margaretten M.E.
        • Kohlwes J.
        • Moore D.
        • et al.
        Does this adult patient have septic arthritis?.
        JAMA. 2007; 297: 1478-1488
        • Hindle P.
        • Davidson E.
        • Biant L.C.
        Septic arthritis of the knee: the use and effect of antibiotics prior to diagnostic aspiration.
        Ann R Coll Surg Engl. 2012; 94: 351-355
        • Goldenberg D.L.
        • Brandt K.D.
        • Cohen A.S.
        • et al.
        Treatment of septic arthritis: comparison of needle aspiration and surgery as initial modes of joint drainage.
        Arthritis Rheum. 1975; 18: 83-90
        • Ravindran V.
        • Logan I.
        • Bourke B.E.
        Medical vs surgical treatment for the native joint in septic arthritis: a 6-year, single UK academic centre experience.
        Rheumatology (Oxford). 2009; 48: 1320-1322
        • Kodumuri P.
        • Geutjens G.
        • Kerr H.L.
        Time delay between diagnosis and arthroscopic lavage in septic arthritis. Does it matter?.
        Int Orthop. 2012; 36: 1727-1731
        • Chen C.M.
        • Lin H.H.
        • Hung S.C.
        • et al.
        Surgical treatment for septic arthritis of the knee joint in elderly patients: a 10-year retrospective clinical study.
        Orthopedics. 2013; 36: e434-e443
        • Sammer D.M.
        • Shin A.Y.
        Comparison of arthroscopic and open treatment of septic arthritis of the wrist.
        J Bone Joint Surg Am. 2009; 91: 1387-1393
        • Abdel M.P.
        • Perry K.I.
        • Morrey M.E.
        • et al.
        Arthroscopic management of native shoulder septic arthritis.
        J Shoulder Elbow Surg. 2013; 22: 418-421
        • Mankovecky M.R.
        • Roukis T.S.
        Arthroscopic synovectomy, irrigation, and debridement for treatment of septic ankle arthrosis: a systematic review and case series.
        J Foot Ankle Surg. 2014; 53: 615-619
        • Moon J.G.
        • Biraris S.
        • Jeong W.K.
        • et al.
        Clinical results after arthroscopic treatment for septic arthritis of the elbow joint.
        Arthroscopy. 2014; 30: 673-678
        • van den Ende K.I.
        • Steinmann S.P.
        Arthroscopic treatment of septic arthritis of the elbow.
        J Shoulder Elbow Surg. 2012; 21: 1001-1005
        • Balabaud L.
        • Gaudias J.
        • Boeri C.
        • et al.
        Results of treatment of septic knee arthritis: a retrospective series of 40 cases.
        Knee Surg Sports Traumatol Arthrosc. 2007; 15: 387-392
        • Hunter J.G.
        • Gross J.M.
        • Dahl J.D.
        • et al.
        Risk factors for failure of a single surgical debridement in adults with acute septic arthritis.
        J Bone Joint Surg Am. 2015; 97: 558-564
        • Lee G.C.
        • Pagnano M.W.
        • Hanssen A.D.
        Total knee arthroplasty after prior bone or joint sepsis about the knee.
        Clin Orthop Relat Res. 2002; : 226-231
        • Peters E.J.
        • Lipsky B.A.
        Diagnosis and management of infection in the diabetic foot.
        Med Clin North Am. 2013; 97: 911-946
        • Kremers H.M.
        • Nwojo M.E.
        • Ransom J.E.
        • et al.
        Trends in the epidemiology of osteomyelitis: a population-based study, 1969 to 2009.
        J Bone Joint Surg Am. 2015; 97: 837-845
        • Cierny 3rd, G.
        • DiPasquale D.
        Treatment of chronic infection.
        J Am Acad Orthop Surg. 2006; 14: S105-S110
        • Cierny 3rd, G.
        Surgical treatment of osteomyelitis.
        Plast Reconstr Surg. 2011; 127: 190S-204S
        • Forsberg J.A.
        • Potter B.K.
        • Cierny 3rd, G.
        • et al.
        Diagnosis and management of chronic infection.
        J Am Acad Orthop Surg. 2011; 19: S8-S19
        • Haidar R.
        • Der Boghossian A.
        • Atiyeh B.
        Duration of post-surgical antibiotics in chronic osteomyelitis: empiric or evidence-based?.
        Int J Infect Dis. 2010; 14: e752-e758
        • Lindbloom B.J.
        • James E.R.
        • McGarvey W.C.
        Osteomyelitis of the foot and ankle: diagnosis, epidemiology, and treatment.
        Foot Ankle Clin. 2014; 19: 569-588
        • Panteli M.
        • Puttaswamaiah R.
        • Lowenberg D.W.
        • et al.
        Malignant transformation in chronic osteomyelitis: recognition and principles of management.
        J Am Acad Orthop Surg. 2014; 22: 586-594
        • Kurtz S.M.
        • Lau E.
        • Watson H.
        • et al.
        Economic burden of periprosthetic joint infection in the United States.
        J Arthroplasty. 2012; 27: 61-65.e1
        • Bozic K.J.
        • Kurtz S.M.
        • Lau E.
        • et al.
        The epidemiology of revision total knee arthroplasty in the United States.
        Clin Orthop Relat Res. 2010; 468: 45-51
        • Bozic K.J.
        • Kurtz S.M.
        • Lau E.
        • et al.
        The epidemiology of revision total hip arthroplasty in the United States.
        J Bone Joint Surg Am. 2009; 91: 128-133
        • Kamath A.F.
        • Ong K.L.
        • Lau E.
        • et al.
        Quantifying the burden of revision total joint arthroplasty for periprosthetic infection.
        J Arthroplasty. 2015; 30: 1492-1497
        • Huotari K.
        • Peltola M.
        • Jamsen E.
        The incidence of late prosthetic joint infections: a registry-based study of 112,708 primary hip and knee replacements.
        Acta Orthop. 2015; 86: 321-325
        • Maoz G.
        • Phillips M.
        • Bosco J.
        • et al.
        The Otto Aufranc Award: modifiable versus nonmodifiable risk factors for infection after hip arthroplasty.
        Clin Orthop Relat Res. 2015; 473: 453-459
        • Muilwijk J.
        • van den Hof S.
        • Wille J.C.
        Associations between surgical site infection risk and hospital operation volume and surgeon operation volume among hospitals in the Dutch nosocomial infection surveillance network.
        Infect Control Hosp Epidemiol. 2007; 28: 557-563
        • Namba R.S.
        • Inacio M.C.
        • Paxton E.W.
        Risk factors associated with deep surgical site infections after primary total knee arthroplasty: an analysis of 56,216 knees.
        J Bone Joint Surg Am. 2013; 95: 775-782
        • Friedman R.J.
        • Hess S.
        • Berkowitz S.D.
        • et al.
        Complication rates after hip or knee arthroplasty in morbidly obese patients.
        Clin Orthop Relat Res. 2013; 471: 3358-3366
        • McElroy M.J.
        • Pivec R.
        • Issa K.
        • et al.
        The effects of obesity and morbid obesity on outcomes in TKA.
        J Knee Surg. 2013; 26: 83-88
        • Duchman K.R.
        • Gao Y.
        • Pugely A.J.
        • et al.
        The effect of smoking on short-term complications following total hip and knee arthroplasty.
        J Bone Joint Surg Am. 2015; 97: 1049-1058
        • Rao N.
        • Cannella B.A.
        • Crossett L.S.
        • et al.
        Preoperative screening/decolonization for Staphylococcus aureus to prevent orthopedic surgical site infection: prospective cohort study with 2-year follow-up.
        J Arthroplasty. 2011; 26: 1501-1507
        • Marchant Jr., M.H.
        • Viens N.A.
        • Cook C.
        • et al.
        The impact of glycemic control and diabetes mellitus on perioperative outcomes after total joint arthroplasty.
        J Bone Joint Surg Am. 2009; 91: 1621-1629
        • Bozic K.J.
        • Lau E.
        • Kurtz S.
        • et al.
        Patient-related risk factors for periprosthetic joint infection and postoperative mortality following total hip arthroplasty in Medicare patients.
        J Bone Joint Surg Am. 2012; 94: 794-800
        • Jiang S.L.
        • Schairer W.W.
        • Bozic K.J.
        Increased rates of periprosthetic joint infection in patients with cirrhosis undergoing total joint arthroplasty.
        Clin Orthop Relat Res. 2014; 472: 2483-2491
        • Peel T.N.
        • Cheng A.C.
        • Buising K.L.
        • et al.
        Microbiological aetiology, epidemiology, and clinical profile of prosthetic joint infections: are current antibiotic prophylaxis guidelines effective?.
        Antimicrob Agents Chemother. 2012; 56: 2386-2391
        • Moran E.
        • Masters S.
        • Berendt A.R.
        • et al.
        Guiding empirical antibiotic therapy in orthopaedics: the microbiology of prosthetic joint infection managed by debridement, irrigation and prosthesis retention.
        J Infect. 2007; 55: 1-7
        • Berbari E.F.
        • Marculescu C.
        • Sia I.
        • et al.
        Culture-negative prosthetic joint infection.
        Clin Infect Dis. 2007; 45: 1113-1119
        • Marculescu C.E.
        • Cantey J.R.
        Polymicrobial prosthetic joint infections: risk factors and outcome.
        Clin Orthop Relat Res. 2008; 466: 1397-1404
        • Richards J.
        • Inacio M.C.
        • Beckett M.
        • et al.
        Patient and procedure-specific risk factors for deep infection after primary shoulder arthroplasty.
        Clin Orthop Relat Res. 2014; 472: 2809-2815
        • Pottinger P.
        • Butler-Wu S.
        • Neradilek M.B.
        • et al.
        Prognostic factors for bacterial cultures positive for Propionibacterium acnes and other organisms in a large series of revision shoulder arthroplasties performed for stiffness, pain, or loosening.
        J Bone Joint Surg Am. 2012; 94: 2075-2083
        • Osmon D.R.
        • Berbari E.F.
        • Berendt A.R.
        • et al.
        Diagnosis and management of prosthetic joint infection: clinical practice guidelines by the Infectious Diseases Society of America.
        Clin Infect Dis. 2013; 56: e1-e25
        • Della Valle C.
        • Parvizi J.
        • Bauer T.W.
        • et al.
        American Academy of Orthopaedic Surgeons clinical practice guideline on: the diagnosis of periprosthetic joint infections of the hip and knee.
        J Bone Joint Surg Am. 2011; 93: 1355-1357
        • Yi P.H.
        • Cross M.B.
        • Moric M.
        • et al.
        The 2013 Frank Stinchfield Award: diagnosis of infection in the early postoperative period after total hip arthroplasty.
        Clin Orthop Relat Res. 2014; 472: 424-429
        • Bedair H.
        • Ting N.
        • Jacovides C.
        • et al.
        The Mark Coventry Award: diagnosis of early postoperative TKA infection using synovial fluid analysis.
        Clin Orthop Relat Res. 2011; 469: 34-40
        • Ghanem E.
        • Parvizi J.
        • Burnett R.S.
        • et al.
        Cell count and differential of aspirated fluid in the diagnosis of infection at the site of total knee arthroplasty.
        J Bone Joint Surg Am. 2008; 90: 1637-1643
        • Omar M.
        • Ettinger M.
        • Reichling M.
        • et al.
        Synovial C-reactive protein as a marker for chronic periprosthetic infection in total hip arthroplasty.
        Bone Joint J. 2015; 97-B: 173-176
        • Deirmengian C.
        • Kardos K.
        • Kilmartin P.
        • et al.
        Combined measurement of synovial fluid alpha-Defensin and C-reactive protein levels: highly accurate for diagnosing periprosthetic joint infection.
        J Bone Joint Surg Am. 2014; 96: 1439-1445
        • Moojen D.J.
        • Spijkers S.N.
        • Schot C.S.
        • et al.
        Identification of orthopaedic infections using broad-range polymerase chain reaction and reverse line blot hybridization.
        J Bone Joint Surg Am. 2007; 89: 1298-1305
        • Kuiper J.W.
        • Willink R.T.
        • Moojen D.J.
        • et al.
        Treatment of acute periprosthetic infections with prosthesis retention: review of current concepts.
        World J Orthop. 2014; 5: 667-676
        • Sherrell J.C.
        • Fehring T.K.
        • Odum S.
        • et al.
        The Chitranjan Ranawat Award: fate of two-stage reimplantation after failed irrigation and debridement for periprosthetic knee infection.
        Clin Orthop Relat Res. 2011; 469: 18-25
        • Prendki V.
        • Zeller V.
        • Passeron D.
        • et al.
        Outcome of patients over 80 years of age on prolonged suppressive antibiotic therapy for at least 6 months for prosthetic joint infection.
        Int J Infect Dis. 2014; 29: 184-189
        • Leonard H.A.
        • Liddle A.D.
        • Burke O.
        • et al.
        Single- or two-stage revision for infected total hip arthroplasty? a systematic review of the literature.
        Clin Orthop Relat Res. 2014; 472: 1036-1042
        • Masters J.P.
        • Smith N.A.
        • Foguet P.
        • et al.
        A systematic review of the evidence for single stage and two stage revision of infected knee replacement.
        BMC Musculoskelet Disord. 2013; 14: 222
        • Shaikh A.A.
        • Ha C.W.
        • Park Y.G.
        • et al.
        Two-stage approach to primary TKA in infected arthritic knees using intraoperatively molded articulating cement spacers.
        Clin Orthop Relat Res. 2014; 472: 2201-2207
        • Voleti P.B.
        • Baldwin K.D.
        • Lee G.C.
        Use of static or articulating spacers for infection following total knee arthroplasty: a systematic literature review.
        J Bone Joint Surg Am. 2013; 95: 1594-1599
        • Mortazavi S.M.
        • Vegari D.
        • Ho A.
        • et al.
        Two-stage exchange arthroplasty for infected total knee arthroplasty: predictors of failure.
        Clin Orthop Relat Res. 2011; 469: 3049-3054
        • Gehrke T.
        • Zahar A.
        • Kendoff D.
        One-stage exchange: it all began here.
        Bone Joint J. 2013; 95-B: 77-83
        • Haddad F.S.
        • Sukeik M.
        • Alazzawi S.
        Is single-stage revision according to a strict protocol effective in treatment of chronic knee arthroplasty infections?.
        Clin Orthop Relat Res. 2015; 473: 8-14
        • Whiteside L.A.
        • Peppers M.
        • Nayfeh T.A.
        • et al.
        Methicillin-resistant Staphylococcus aureus in TKA treated with revision and direct intra-articular antibiotic infusion.
        Clin Orthop Relat Res. 2011; 469: 26-33
        • Antony S.J.
        • Westbrook R.S.
        • Jackson J.S.
        • et al.
        Efficacy of single-stage revision with aggressive debridement using intra-articular antibiotics in the treatment of infected joint prosthesis.
        Infect Dis (Auckl). 2015; 8: 17-23
        • Parvizi J.
        • Adeli B.
        • Zmistowski B.
        • et al.
        Management of periprosthetic joint infection: the current knowledge: AAOS exhibit selection.
        J Bone Joint Surg Am. 2012; 94: e104
        • Kubista B.
        • Hartzler R.U.
        • Wood C.M.
        • et al.
        Reinfection after two-stage revision for periprosthetic infection of total knee arthroplasty.
        Int Orthop. 2012; 36: 65-71
        • Mahmud T.
        • Lyons M.C.
        • Naudie D.D.
        • et al.
        Assessing the gold standard: a review of 253 two-stage revisions for infected TKA.
        Clin Orthop Relat Res. 2012; 470: 2730-2736
        • Siqueira M.B.
        • Saleh A.
        • Klika A.K.
        • et al.
        Chronic suppression of periprosthetic joint infections with oral antibiotics increases infection-free survivorship.
        J Bone Joint Surg Am. 2015; 97: 1220-1232