Keywords
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.
Content published before 2002 is available via pay-per-view purchase only.
Subscribe:
Subscribe to Clinics in Geriatric MedicineReferences
- Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II.Arthritis Rheum. 2008; 58: 26-35
US Centers for Disease Control and Prevention. National diabetes statistics report, 2014. Estimates of diabetes and its burden in the United States fact sheet. Available at: http://www.cdc.gov/diabetes/pubs/estimates14.htm. Accessed July 14, 2014.
- Prevalence of doctor-diagnosed arthritis and arthritis-attributable activity limitation – United States, 2007-2009.MMWR Morb Mortal Wkly Rep. 2010; 59: 1261-1265
Centers for Disease Control and Prevention. 2011 national diabetes fact sheet. 2011. Available at: http://www.cdc.gov/diabetes/pubs/factsheet11.htm. Accessed February 10, 2014.
- Diabetes is an independent predictor for severe osteoarthritis: results from a longitudinal cohort study.Diabetes Care. 2013; 36: 403-409
- Non-insulin dependent diabetes mellitus (NIDDM) and patterns of osteoarthritis.Scand J Rheumatol. 2001; 30: 169-171
- Arthritis as a potential barrier to physical activity among adults with diabetes - United States, 2005 and 2007.MMWR Morb Mortal Wkly Rep. 2008; 57: 486-489
- Association of osteoarthritis and diabetes mellitus.Tufts Folia Med. 1961; 7: 13-19
- Longevity of human islet α-and β-cells.Diabetes Obes Metab. 2001; 13: 39-46
- Diabetes-induced osteoarthritis: from a new paradigm to a new phenotype.Ann Rheum Dis. 2011; 70: 1354-1356
- Aging: a theory based on free radical and radiation chemistry.J Gerontol. 1956; 11: 298-300
- The biologic clock: the mitochondria?.J Am Geriatr Soc. 1972; 20: 145-147
- Decline in skeletal muscle mitochondrial respiratory chain function: possible factor in ageing.Lancet. 1989; 1: 637-639
- Mechanisms linking obesity to insulin resistance and type 2 diabetes.Nature. 2006; 444: 840-846
- Osteoarthritis and cartilage: the role of cytokines.Curr Rheumatol Rep. 2000; 2: 459-465
- Risk factors for incident radiographic knee osteoarthritis in the elderly: the Framingham study.Arthritis Rheum. 1997; 40: 728-733
- Body mass index associated with onset and progression of osteoarthritis of the knee but not of the hip: the Rotterdam study.Ann Rheum Dis. 2007; 66: 158-162
- The mechanism of the effect of obesity in knee osteoarthritis: the mediating role of malalignment.Arthritis Rheum. 2000; 43: 568-575
- Obesity and osteoarthritis of the knee: hypotheses concerning the relationship between ground reaction forces and quadriceps fatigue in long-duration walking.Med Hypotheses. 2000; 54: 182-185
- Reduced quadriceps strength relative to body weight: a risk factor for knee osteoarthritis in women?.Arthritis Rheum. 1998; 41: 1951-1959
- Is osteoarthritis a metabolic disease?.Joint Bone Spine. 2013; 80: 568-573
- The role of cytokines in osteoarthritis pathophysiology.Biorheology. 2002; 39: 237-246
- Change in body fat, but not body weight or metabolic correlates of obesity, is related to symptomatic relief of obese patients with knee osteoarthritis after a weight control program.J Rheumatol. 1998; 25: 2181-2186
- Evidence for a key role of leptin in osteoarthritis.Arthritis Rheum. 2003; 48: 3118-3129
- Leptin enhances MMP-1, MMP-3 and MMP-13 production in human osteoarthritic cartilage and correlates with MMP-1 and MMP-3 in synovial fluid from OA patients.Clin Exp Rheumatol. 2011; 29: 57-64
- Increased serum adiponectin levels in female patients with erosive compared with non-erosive osteoarthritis.Ann Rheum Dis. 2009; 68: 295-296
- Association between leptin, adiponectin and resistin and long-term progression of hand osteoarthritis.Ann Rheum Dis. 2011; 70: 1282-1284
- Adipokines and osteoarthritis: novel molecules involved in the pathogenesis and progression of disease.Arthritis. 2011; 2011: 203901
- National High Blood Pressure Education Program Working Group report on hypertension in diabetes.Hypertension. 1994; 23: 145-158
- Risk factors for development of diabetes mellitus, hypertension and dyslipidemia.Diabetes Res Clin Pract. 2011; 94: e15-e18
- Association between metabolic factors and knee osteoarthritis in women: the Chingford study.J Rheumatol. 1995; 22: 1118-1123
- Osteoarthritis: another component of metabolic syndrome?.Metab Syndr Relat Disord. 2010; 8: 295-305
- Metabolic syndrome meets osteoarthritis.Nat Rev Rheumatol. 2012; 8: 729-737
- Vascular pathology and osteoarthritis.Rheumatology. 2007; 46: 1763-1768
- Increased prevalence of metabolic syndrome in individuals with osteoarthritis: an analysis of NHANES III data.Postgrad Med. 2009; 121: 9-20
- C-reactive protein, metabolic syndrome and incidence of severe hip and knee osteoarthritis. A population-based cohort study.Osteoarthr Cartil. 2009; 17: 168-173
- Comorbid disease profiles of adults with end-stage hip osteoarthritis.Med Sci Monit. 2002; 8: CR305-CR309
- Is progressive osteoarthritis an atheromatous vascular disease?.Ann Rheum Dis. 2005; 64: 1539-1541
- The association of lipid abnormalities with tissue pathology in human osteoarthritic articular cartilage.Metabolism. 1991; 40: 571-576
- Lipid metabolism and osteoarthritis: lessons from atherosclerosis.Prog Lipid Res. 2011; 50: 133-140
- Lectin-like oxidized low density lipoprotein receptor 1 (LOX-1) expression in human articular chondrocytes.Clin Exp Rheumatol. 2007; 25: 605-612
- Effect of fatty acids on bone marrow lesions and knee cartilage in healthy, middle-aged subjects without clinical knee osteoarthritis.Osteoarthr Cartil. 2008; 16: 579-583
- High levels of fat and (n-6) fatty acids in cancellous bone in osteoarthritis.Lipids Health Dis. 2004; 3: 12
- Bone marrow edema and its relation to progression of knee osteoarthritis.Ann Intern Med. 2003; 139: 330-336
- Functional consequences of sarcopenia and dynapenia in the elderly.Curr Opin Clin Nutr Metab Care. 2010; 13: 271-276
- Predictors of 6-minute walk test results in lean, obese and morbidly obese women.Scand J Med Sci Sports. 2003; 13: 98-105
- The effect of surgical weight reduction on functional status in morbidly obese patients with low back pain.Obes Surg. 2005; 15: 378-381
- Plantar pressure differences between obese and non-obese adults: a biomechanical analysis.Int J Obes Relat Metab Disord. 2001; 25: 1674-1679
- Pain in the obese: impact on health-related quality-of-life.Ann Behav Med. 1997; 19: 408-410
- The effect of noninsulin dependent diabetes mellitus on the prevalence of clinical osteoarthritis: a population based study.J Rheumatol. 1996; 23: 716-722
- Osteophyte formation in diabetic patients with OA.Arthritis Rheum. 1992; 35: 336-342
- Association of hand or knee osteoarthritis with diabetes mellitus in a population of Hispanics from Puerto Rico.J Clin Rheumatol. 2013; 19: 1-6
- Glucose transport and metabolism in chondrocytes: a key to understanding chondrogenesis, skeletal development and cartilage degradation in osteoarthritis.Histol Histopathol. 2002; 17: 1239-1267
- Impaired glucose transporter-1 degradation and increased glucose transport and oxidative stress in response to high glucose in chondrocytes from osteoarthritic versus normal human cartilage.Arthritis Res Ther. 2009; 11: R80
- Impact of diabetes and its treatments on skeletal diseases.Front Med. 2013; 7: 81-90
- Update on the biology of the chondrocyte and new approaches to treating cartilage diseases.Best Pract Res Clin Rheumatol. 2006; 20: 1003-1025
- Role of glucose as a modulator of anabolic and catabolic gene expression in normal and osteoarthritic human chondrocytes.J Cell Biochem. 2011; 112: 2813-2824
- Increased fasting serum glucose concentration is associated with adverse knee structural changes in adults with no knee symptoms and diabetes.Maturitas. 2012; 72: 373-378
- Biochemistry and molecular cell biology of diabetic complications.Nature. 2001; 414: 813-820
- Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis.Arthritis Rheum. 2002; 46: 114-123
- Age-related accumulation of Maillard reaction products in human articular cartilage collagen.Biochem J. 2000; 350: 381-387
- Activation of receptor for advanced glycation end products in osteoarthritis leads to increased stimulation of chondrocytes and synoviocytes.Arthritis Rheum. 2006; 54: 253-263
- Does diabetes hide osteoarthritis pain?.Med Hypotheses. 2012; 78: 471-474
- Proprioception in knee osteoarthritis: a narrative review. 2011.Osteoarthr Cartil. 2011; 19: 381-388
- Positron emission tomography with 18F-FDG in osteoarthritic knee.Osteoarthr Cartil. 2007; 15: 673-681
- (18F)Fluoro-deoxy-D-glucose uptake of knee joints in the aspect of age- related osteoarthritis: a case-control study.BMC Musculoskelet Disord. 2013; 14: 141
- Treatment of osteoarthritis of the knee: evidence-based guideline, 2nd edition.J Am Acad Orthop Surg. 2013; 21: 571-576
- OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines.Osteoarthr Cartil. 2008; 16: 137-162
- American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee.Arthritis Care Res. 2012; 64: 465-474
- Exercise and type 2 diabetes: American College of Sports Medicine and the American Diabetes Association: joint position statement. Exercise and type 2 diabetes.Med Sci Sports Exerc. 2010; 42: 2282-2303
US Department of Health and Human Services. 2008 Physical activity guidelines for Americans. Available at: http://www.health.gov/paguidelines/. Accessed February 11, 2014.
Agency for Healthcare Research and Quality. Physical activity and older Americans: benefits and strategies. Available at: http://www.innovations.ahrq.gov/content.aspx?id=991. Accessed February 11, 2014.
- Summary of the updated American Geriatrics Society/British Geriatrics Society clinical practice guideline for prevention of falls in older persons.J Am Geriatr Soc. 2011; 59: 148-157
- The impact of exercise training compared to caloric restriction on hepatic and peripheral insulin resistance in obesity.J Clin Endocrinol Metab. 2009; 94: 4258-4266
- Free fatty acid-induced hepatic insulin resistance is attenuated following lifestyle intervention in obese individuals with impaired glucose tolerance.J Clin Endocrinol Metab. 2010; 95: 323-327
- Effects of exercise training and diet on lipid kinetics during free fatty acid-induced insulin resistance in older obese humans with impaired glucose tolerance.Am J Physiol Endocrinol Metab. 2009; 297: E552-E559
- Anti-inflammatory effect of exercise training in subjects with type 2 diabetes and the metabolic syndrome is dependent on exercise modalities and independent of weight loss.Nutr Metab Cardiovasc Dis. 2010; 20: 608-617
- Effects of resistance or aerobic exercise training on interleukin-6, C-reactive protein, and body composition.Med Sci Sports Exerc. 2010; 42: 304-313
- Effect of exercise training on interleukin-6, tumour necrosis factor alpha and functional capacity in heart failure.Cardiol Res Pract. 2011; 2011: 532620
- Combined endurance/resistance training reduces plasma TNF-alpha receptor levels in patients with chronic heart failure and coronary artery disease.Eur Heart J. 2002; 23: 1854-1860
- The impact of training modalities on the clinical benefits of exercise intervention in patients with cardiovascular disease risk or type 2 diabetes mellitus.Sports Med. 2010; 40: 921-940
- A systematic review of the separate and combined effects of energy restriction and exercise on fat-free mass in middle-aged and older adults: implications for sarcopenic obesity.Nutr Rev. 2010; 68: 375-388
- Exercise and older patients: prescribing guidelines.Am Fam Physician. 2006; 74: 437-444
- Resistance exercise in individuals with and without cardiovascular disease: 2007 update: a scientific statement from the American Heart Association Council on Clinical Cardiology and Council on Nutrition, Physical Activity, and Metabolism.Circulation. 2007; 116: 572-584
- Physical activity guidelines for older adults.Am Fam Physician. 2010; 81: 55-59
- American College of Sports Medicine Position Stand. Appropriate physical activity intervention strategies for weight loss and prevention of weight regain for adults.Med Sci Sports Exerc. 2009; 41: 459-471
- Dose response between physical activity and risk of coronary heart disease: a meta-analysis.Circulation. 2011; 124: 789-795
- Exercise training, lipid regulation, and insulin action: a tangled web of cause and effect.Obesity (Silver Spring). 2009; 17: S21-S26
- Longterm physical training in rheumatoid arthritis. A randomized trial with different training programs and blinded observers.Scand J Rheumatol. 1993; 22: 107-112
- Exercise, abdominal obesity, skeletal muscle, and metabolic risk: evidence for a dose response.Obesity. 2009; 17: S27-S33
- Comparing physical activity programs for managing osteoarthritis in overweight or obese patients.J Comp Eff Res. 2014; 3: 283-299
- Standards of medical care in diabetes–2007.Diabetes Care. 2007; 30: S4-S41
- Clinician's guide to cardiopulmonary exercise testing in adults: a scientific statement from the American Heart Association.Circulation. 2010; 122: 191-225
- ACSM's guidelines for exercise testing and prescription.Lippincott Williams and Wilkins, Baltimore (MD)2010
- Exercise assessment and prescription in patients with type 2 diabetes in the private and home care setting: clinical recommendations from AXXON (Belgian Physical Therapy Association).Phys Ther. 2013; 93: 597-610
- Weight change and the conservation of lean mass in old age: the health, aging and body composition study.Am J Clin Nutr. 2005; 82 ([quiz: 915–6]): 872-878
- Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis: the arthritis, diet, and activity promotion trial.Arthritis Rheum. 2004; 50: 1501-1510
- Effects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcomes among overweight and obese adults with knee osteoarthritis: the IDEA randomized clinical trial.JAMA. 2013; 310: 1263-1273
- Intensive weight loss program improves physical function in older obese adults with knee osteoarthritis.Obesity (Silver Spring). 2006; 14: 1219-1230
- Moderate exercise attenuates the loss of skeletal muscle mass that occurs with intentional caloric restriction-induced weight loss in older, overweight to obese adults.J Gerontol A Biol Sci Med Sci. 2009; 64: 575-580
- Determinants of high and low attendance to diet and exercise interventions among overweight and obese older adults. Results from the arthritis, diet, and activity promotion trial.Contemp Clin Trials. 2006; 27: 227-237
- Primary osteoarthritis no longer primary: three subsets with distinct etiological, clinical, and therapeutic characteristics.Semin Arthritis Rheum. 2009; 39: 71-80
Mayo Clinic. Risk factors for diabetes. 2013. Available at: http://www.mayoclinic.org/diseases- conditions/diabetes/basics/risk-factors/con-20033091. Accessed January 2, 2014.
Centers for Disease Control and Prevention. Osteoarthritis risk factors. 2014. Available at: http://www.cdc.gov/arthritis/basics/risk-factors.htm. Accessed January 2, 2014.
- Physical activity/exercise and type 2 diabetes: a consensus statement from the American Diabetes Association.Diabetes Care. 2006; 29: 1433-1438