Food is essential to survival and health. Our ability to expend energy depends on
adequate intake of protein and calories; however, even when adequate calories are
available, nutritional deficiency diseases can occur. Historically, physicians observed
that a number of peculiar disease states, such as scurvy, pellagra, and beriberi,
were directly related to dietary intake. These diseases were found even in the presence
of adequate calorie and protein intake. These strange nutritional deficiency states
perplexed researchers until the turn of the century.
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References
- Can antioxidant vitamins materially reduce oxidative damage in humans?.Free Radic Biol Med. 1999; 26: 1034-1053
- Dietary intake, dietary patterns, and changes with age: an epidemiological perspective.J Gerontol A Biol Sci Med Sci. 2001; 56: 65-80
- Impact of aging on eating behaviors, food choices, nutrition, and health status.J Nutr Health Aging. 2001; 5: 75-79
- Vegetable and fruit intake and stroke mortality in the Hiroshima/Nagasaki life span study.Stroke. 2003; 34: 2355-2360
- Homocyst(e)ine and cardiovascular disease: a critical review of the epidemiologic evidence.Ann Intern Med. 1999; 131: 363-375
- Vitamin supplement use in a low-risk population of US male physicians and subsequent cardiovascular mortality.Arch Intern Med. 2002; 162: 1472-1476
- Dietary factors and pulmonary function: a cross sectional study in middle aged men from three European countries.Thorax. 1999; 54: 1021-1026
- Serum vitamins and the subsequent risk of bladder cancer.J Urol. 2003; 170: 1146-1150
- Antioxidant vitamin intake and risk of Alzheimer disease.Arch Neurol. 2003; 60: 203-208
- Routine vitamin supplementation to prevent cardiovascular disease: a summary of the evidence for the US Preventive Services Task Force.Ann Intern Med. 2003; 139: 56-70
- MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: a randomised placebo-controlled trial.Lancet. 2002; 360: 23-33
- Antioxidant vitamins and lipid therapy—end of a long romance?.Arterioscler Thromb Vasc Biol. 2002; 22: 1535-1546
- Drugs for preventing lung cancer in healthy people.Cochrane Database Syst Rev. 2003; 3
- Vitamin C supplementation for asthma.Cochrane Database Syst Rev. 2003; 3
- Vitamins for chronic disease prevention in adults—scientific review.JAMA. 2002; 287: 3116-3126
- Antioxidant vitamins in the prevention of cardiovascular disease: a systematic review.J Intern Med. 2002; 251: 372-392
- Homocyst(e)ine and risk of cerebral infarction in a biracial population: the stroke prevention in young women study.Stroke. 1999; 30: 1554-1560
- Intake of flavonoids, carotenoids, vitamins C and E, and risk of stroke in male smokers.Stroke. 2000; 31: 2301-2306
- Low circulating folate and vitamin B-6 concentrations: risk factors for stroke, peripheral vascular disease, and coronary artery disease.Circulation. 1998; 97: 437-443
- Plasma homocysteine predicts mortality independently of traditional risk factors and C-reactive protein in patients with angiographically defined coronary artery disease.Circulation. 2000; 102: 1227-1232
- Vitamin supplement use in a low-risk population of US male physicians and subsequent cardiovascular mortality.Archives of Internal Medicine. 2002; 162: 1472-1476
- Serum antioxidant vitamins and blood pressure in the United States population.Hypertension. 2002; 40: 810-816
- Dietary factors and pulmonary function: a cross sectional study in middle aged men from three European countries.Thorax. 1999; 54: 1021-1026
- Serum vitamins and the subsequent risk of bladder cancer.Journal of Urology. 2003; 170: 1146-1150
- Antioxidant vitamin intake and risk of Alzheimer disease.Archives of Neurology. 2003; 60: 203-208
- MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: a randomised placebo-controlled trial.Lancet. 2002; 360: 23-33
- Ascorbic acid reduces blood pressure and arterial stiffness in type 2 diabetes.Hypertension. 2002; 40: 804-809
- Lack of long-term effect of vitamin C supplementation on blood pressure.Hypertension. 2002; 40: 797-803
- Effects of a short-term vitamin D3 and calcium supplementation on blood pressure and parathyroid hormone levels in elderly women.Journal of Clinical Endocrinology & Metabolism. 2001; 86: 1633-1637
- Vitamin C supplementation for asthma.Cochrane Database of Systematic Reviews. 2003;
- Drugs for preventing lung cancer in healthy people.Cochrane Database of Systematic Reviews. 2003;
- Effects of a combination of beta-carotene and vitamin A on lung cancer and cardiovascular disease.N Engl J Med. 1996; 334: 1150-1155
- Incidence of Cancer and Mortality Following alpha-Tocopherol and beta-carotene Supplementation: A Postintervention Follow-up.JAMA. 2003; 290: 476-485
- MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20536 high-risk individuals.Lancet. 2002; 360: 23-33
- A Clinical Trial of Antioxidant Vitamins To Prevent Colorectal Adenoma.NEJM. 1994; 331: 141-147
- A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. The Alzheimer's Disease Cooperative Study.New England Journal of Medicine. 1997; 336: 1216-1222
- Thiamine for Alzheimer's disease.Cochrane Database of Systematic Reviews. 2003;
- Vitamin B6 as add-on treatment in chronic schizophrenic and schizoaffective patients: a double-blind, placebo-controlled study.Journal of Clinical Psychiatry. 2002; 63: 54-58
- Folate for depressive disorders.The Cochrane Database of Systematic Reviews. 2003;
- A randomized trial of beta-carotene and age-related cataract in US physicians.Archives of Ophthalmology. 2003; 121: 372-378
- Antioxidant vitamin and mineral supplements for age-related macular degeneration.Cochrane Database of Systematic Reviews. 2003;
- Impact of trace elements and vitamin supplementation on immunity and infections in institutionalized elderly patients: a randomized controlled trial.Archives of Internal Medicine. 1999; 159: 748-754
- Effect of vitamin and trace-element supplementation on immune responses and infection in elderly subjects.Lancet. 1992; 340: 1124-1127
- Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis.Cochrane Database of Systematic Reviews. 2003;
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© 2004 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
